The café where the three ladies meet and Diane introduces Oscar to her friends was also the location where director Gary Winick arranged a meeting with Sigourney Weaver before production, to play the part of Eve. After Weaver spoke to the restaurant owner, they agreed to let them use it in the film.
Diane's apartment is actually Gary Winick's mother's apartment.
The name "Tadpole" came from the game Pictionary. The whole film was shot in about two weeks.
The film was criticized at the Sundance Festival for its poor technical quality. It was shot on video and suffered from blown out backgrounds, inconsistent color, poor night shots, etc.
The film was shot in 14 days. Sigourney Weaver worked for 10 of those days.